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Archiver > GENEALOGY-DNA > 2001-07 > 0994224958


From: "Bob Durham" <>
Subject: RE: [DNA] Surname DNA Projects
Date: Tue, 3 Jul 2001 22:35:58 -0700
In-Reply-To: <25.178e33d8.28736f42@aol.com>


Hi Ann:

We would anticipate classifying Y-STR locus
information as follows:

Locus Motif #repeats #alleles
DYS193) (GATA)n 12-18 10 174-210 0.72 2.01 x 10-3
(0.26 - 6.82 x 10-3)
DYS389I4) (GATA)n(GACA)n 10-15 6 235-263 0.61 2.35 x 10-3
(0.06 - 12.5 x 10-3)
DYS389II4) (GATA)n(GACA)n 26-34 9 355-383 0.75 4.71 x 10-3
(0.6 - 16.0 x 10-3)
DYS390 (GATA)n(GACA)n 20-27 8 191-227 0.61 8.58 x 10-3
(2.54 - 20.3 x 10-3)
DYS391 (GATA)n 8-13 6 271-299 0.49 4.82 x 10-3
(0.61 - 16.4 x 10-3)
DYS392 (ATT)n 8-18 11 233-263 0.52 0 (7.15 x 10-3)
DYS393 (GATA)n 12-17 6 108-136 0.34 0 (7.15 x 10-3)
DYS3855) (GAAA)n 8-21 62 352-412 0.85 2.10 x 10-3
(0.27 - 7.15 x 10-3)

...where DYS indicates the Locus; Alleles & Base Pairs are enumerated.

The STR nomenclature follows the model most recently published in 1997:

Reference tables to:
Evaluation of Y-chromosomal STRs: a multicenter study (Kayser et al.) and
Chromosome Y microsatellites: population genetic and evolutionary aspects
(de Knijff et al.)
Int J Leg Med 110 (1997) 3, 141-149
(http://link.springer.de/link/service/journals/00414/bibs/7110003/71100141.h
tm)

for those STR sequences that are new/unique/proprietary, and are not yet
classified,
I am not sure what to recommend. Obviously the ideal thing would be for
these STR
sequence identifications to fall within the same nomenclature for
identification;
perhaps someone on the list knows what process is used to encapsulate
these...

In any event, my curiosity is piqued enough to take a closer look.

Bob.

-----Original Message-----
From: [mailto:]
Sent: Tuesday, July 03, 2001 11:56 AM
To:
Subject: Re: [DNA] Surname DNA Projects


In a message dated 07/03/01 7:36:24 AM Pacific Daylight Time,
writes:


> 2) Agenus.com can build STR test results and surname entry forms
> for entering data in to the database.

This sounds like an interesting concept. How do you propose to handle the
different STRs used by various testing companies? There's some overlap, of
course, but also some STRs are unique to each company.



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