GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2002-02 > 1013641307
From: Brett Miller <>
Subject: Re: [DNA] Re: mtDNA Question
Date: Wed, 13 Feb 2002 15:01:58 -0800 (PST)
I missed this follow-up question earlier, so let me
The Maternal Ancestry Signature is the mtDNA
sequencing of HVS1 and HVS2 and the Native American
test is the mtDNA Haplotype using RFLP (enzyme).
Our mtDNA sequence is as follows:
HVS1: 16100 - 16569
HVS2: 1 - 290
The sequence vs. haplotype is a tough question. A
haplogroup test is used to determine the A-D,X and the
sequence is used to determine a sub-group if any. So
if the person is in a subgroup, then that will show up
on the sequencing test and will be just as reliable as
a haplogroup (enzyme) test. However, some people may
not have a subgroup that shows up in the sequence test
so it might look like they are not Native American,
even though a enzyme test would show that they are. I
don't have enough information to know how many people
would get a false negative result on the sequencing
test. If anyone else has seen statistics on this I'd
love to read them.
> So if you order the "Maternal Ancestry" signature,
> you get the mtDNA sequence
> and if you order the "Native American" signature you
> get the haplotype enzyme
> Which bases are included in the mtDNA sequence?
> OxAnc and FTDNA report
> The mtDNA sequence test might give you enough
> information to decide if you're
> in haplogroup A-D or X. How likely are you to get
> different information from
> the haplotype enzyme test?
> Ann Turner
> GENEALOGY-DNA List Administrator
> To join Ancestry.com and access our 1.2 billion
> online genealogy records, go to:
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