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Archiver > GENEALOGY-DNA > 2002-03 > 1015011523


From: "Nancy Custer " <>
Subject: RE: [DNA] Results Comments?
Date: Fri, 1 Mar 2002 11:38:43 -0800
In-Reply-To: <01C1C112.86801E80.mmay@richmark.com>


You are a rare bird Mark! According to my queries of the USA, European,
and Asian databases at www.ystr.org, your DYS390 value of 20 had the
following matches

DYS390 = 20
USA 15 hits (all African American*) frequency = .0088 (n = 1705)
European 8 hits frequency = .0009 (n =
8592)
Asia 7 hits frequency = .0041 (n =
1721)
Total30 hits frequency = .0025 (n =
12,018)

*599 African Americans sampled frequency = .0250

I have a graph of the US and European frequencies for DYS390 at
http://www.contexo.info/FUS&Ecombined.htm#DYS390 As you will see, you
barely make the graph! I suppose I should do the Asian database now
too:(

Have you linked your paternal line to a European ancestor from a known
location? I'm not a molecular geneticist or a population geneticist so
maybe this is a naïve (read stupid) question. Even though we can't
"known" the answer, I'd be interested in hearing discussion on it.
Would this close affinity to African and Asian values in a person of
European descent most likely suggest a big "back mutation" or could it
be a random preservation of a very ancient allele? Do we know enough to
make a guess?

Also, the AMH for DYS390 is 24. A score of 20 suggests four mutations,
doesn't it? Does that mean you have five mutations in the other
alleles? Or does this mean I am using a simplistic assumption about
what a mutation is?

Your results are interesting. Thanks for sharing them. Are the other
alleles interesting too?

Nancy
www.contexo.info

-----Original Message-----
From: Mark May [mailto:]
Sent: Friday, March 01, 2002 9:16 AM
To:
Subject: RE: [DNA] Results Comments?

I have been doing the same with my DYS390 score, which also seems to be
rare. My score is 20. This score gets very few hits on any database,
but
seems to come up for east Asians a bit more than other groups. As far
as I
know I am European roots, but because of DYS 390 I am 9 mutations off
the
AMH.

J Mark May

-----Original Message-----
From:Kenneth V. Graves [SMTP:]
Sent:Friday, March 01, 2002 8:07 AM
To:
Subject:Re: [DNA] Results Comments?

Gregg Bonner wrote:
<The reason I say I think my 390 value is rare is not based on a
semi-scientific analysis of the Y-STR, but rather just going about the
individual project pages and looking in the results tables for a
DYS390=23
value. Seeing none, I concluded (evidently incorrectly) that 23 is rare
for
DYS390 (most were DYS390=24).>

Checking the first 79 test results from the Graves/Greaves study, I find
that 24 of the 79 have a DYS390 value of 23, 5 are 25, 1 is 22, and the
remaining 49 are 24.

Ken Graves


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