GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2002-04 > 1018486401


From: Colleen Lopez <>
Subject: Re: [DNA] Help I'm a "G" and i don't know what that means
Date: Wed, 10 Apr 2002 17:53:30 -0700 (PDT)
In-Reply-To: <20020410220447.9063.qmail@web21305.mail.yahoo.com>


Thanks so much, from what I could read apparently the "Helen" daughter of Eve came from the Pyrenees area of France and migrated north towards England and can be found through out Europe. This is interesting. I can't wait to get my dad's dna results back. I always thought we carried parts of all of our ancesters in us, both the father's and mothers side. My father's Norwegian and Prussian and German, my mother well, she's "Castilian", english and german- jew- danish?. Now I found out I only carry my original ancester's attributes. You would think that more of us all looked a little more alike wouldn't you? Like my mom has green eyes, my dad has hazel. I have brown. Both of them are right handed I am left. I know a recessive gene is there, but to break it down into one of seven (Eve's daughter's) seems almost impossible doesn't it?
I really appreciate your help. If you think I might have a match somewhere feel free to keep my "DNA" print on file! Again, thanks so much.
I was trying to find out what "G" was more prone to as far as deseases. Like in my case I have pernicious anemia a type of auto immune disease. I get a B12 shot every month and that takes care of it. But no one to our knowledge has ever had that in the family save a grgr uncle. I also suffer from fybromayalgia and CFS with Interstitial Cystitis. You see why I want to research this a little more. (all of the aforementioned have to do with autoimmune problems.) Not AIDS! this is something entirely different. My immunities work overtime!
Well thank you for your time, I guess you can't get more personal than your DNA print huh?
Sincerely Colleen
Brett Miller <> wrote: Well, the G is the Guanine DNA base substitution not
Haplogroup G. The Revised Cambridge Reference
Sequence has an 'A' in position 263 while your DNA has
a 'G' in that position. This is called a mutation (at
least compared to the RCRS).

If you look at the chart at:
http://www.stats.ox.ac.uk/~macaulay/founder2000/motif.html
Since you do not have any mutations in HVR-1 and no
mutation at positoin 72 (CRS is 'A' at position 73),
you are in haplogroup H (or HV, I can't tell the
difference from that chart). I think that is 'Helena'
in Sykes Severn Daughters of Eve lingo.

If you go to:
http://www.gen.emory.edu/MITOMAP/WorldMigrations.pdf
You can see migration patterns of the various
haplogroups. Haplogroup H appears to be found mostly
in northern Europe.

If you go to the Mitochondrial Concordance at:
http://shelob.bioanth.cam.ac.uk/mtDNA/toc.html
and click the 250-263 range, and scroll down some,
you'll see 263 in red. It is a common mutation in
many of the studies conducted. Since you had no other
mutations in the ranges tested, you can focus on the
studies that have a 263G mutation and no other
mutations in the range tested. Go to the bottom where
263G is the first mutation listed. Exclude any rows
that have a mutations in the range tested (1 - 290).
You can include any rows that have mutations outside
the tested range becuase we don't know if you have
mutations of not in the 3xx range. Now look to the
far right where it says Tuscan or UK. These are where
this mutation has shown up in these published
population/DNA studies, and should give you some idea
of where your maternal line originated from.

That's my best interpretation from what I understand
from all the different data sources.



--- Colleen Lopez wrote:
> My name is Colleen, I have a natural gold skin tan
> and have dark eyes and rather petite.(for genealogy
> dna ref only) Listed below are the full results I
> received. I guess I matched the Cambridge system or
> what ever except in position 263 value G, RCRS A,
> Region HVR-2
> Now if any one can explain that to me, I would
> really appreciate it! I looked up the "G" migration
> pattern which lead from Africa into Asia, however,
> to my knowledge or even appearance I am of no asian
> heritage? We questioned if we had "Jewish" roots or
> not before because of the names from Germany through
> my Maternal side. The Labs told me that I was the
> only "G" they ever received. Now if that doesn't
> make you feel alone what will! smiles.....
> Can someone explain this to me?
> Thank-you Colleen


__________________________________________________
Do You Yahoo!?
Yahoo! Tax Center - online filing with TurboTax
http://taxes.yahoo.com/


==============================
To join Ancestry.com and access our 1.2 billion online genealogy records, go to:
http://www.ancestry.com/rd/redir.asp?targetid=571&sourceid=1237



Colleen Lopez, Israel Tour Specialist, Christains For Israel Rep.

Please check my link for any information you may need regarding Israel or ways you can support Israel to include links to congress, in "links of support" at ForZionsSakeOnline.org

"For Zions Sake, I will not hold my peace!" Isaiah 62:1

"I will bless them that bless thee and curse them that curse thee, in thee shall all the families of the earth be blessed." Gen 12:3

"Pray for the peace of Jerusalem!" Psalm 122:6



---------------------------------
Do You Yahoo!?
Yahoo! Tax Center - online filing with TurboTax

This thread: