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Archiver > GENEALOGY-DNA > 2002-04 > 1018756380


From: "Orin R. Wells" <>
Subject: Re: [DNA] XYY Karyotype
Date: Sat, 13 Apr 2002 20:57:16 -0800
In-Reply-To: <3CB8F349.EDD0A76B@pars.net>


At 10:11 PM 4/13/02 -0500, Philip Lindsey wrote:

> I haven't seen this addressed before, but perhaps someone can chime
>in and help me out. I have a friend (a pathology instructor, as it were)
>who is XYY karyotypic.
> I would like to discuss the whole DNA Ystr genealogy subject with
>him but am puzzled about what to say if the subject turns to its
>application to him.<<

I am going to stick my neck out and guess the answer here. I am sure
someone with the real knowledge will step in and tell us if I am wrong.

The only way an embryo can get an extra Y chromosome is if it comes from
the father because the mother doesn't have any to give. Since the father
normally has only one "Y" chromosome, as this is not something typically
passed on from father to son, it seems logical that both that end up in the
embryo will be identical. So I would guess that the person could easily
have a y-chromosome test and have it come out OK and it would provide the
same level of information that those of us who are short the extra "Y"
would see. I have also seen this called a creative "XYY Male Syndrome"

I am aware of a Wells who has this syndrome. He is a professor at one of
the universities, so apparently it hasn't caused him any problems. He
isn't in my study, but his brother is (was, he died on us unfortunately
revealing a heart valve problem in his family I didn't know about).

Things that tend to impact the XYY people is a tendency to slow learning,
very physically active (jocks), above average height (2.5+ inches
taller). Otherwise they are pretty normal. The rate seems to be about 1
in 1,000 births and most go through life not knowing they have the syndrome.


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