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From:
Subject: Re: [DNA] Irish versus Norwegian R1b Signatures [YCA II]
Date: Wed, 3 Dec 2003 11:39:05 EST
In a message dated 12/03/03 8:15:35 AM Pacific Standard Time,
writes:
> Shane: I take it then that you input only the 8 markers beginning with
> DYS19(394) and ending with DYS385 (with its biallelic 2 markers a and b), but
> did not input the next biallelic marker option YCAII on their search option
> button array at the top of the page. It is equivalent to FTDNAs DYS389-1 and
> DYS389-2.
??? You must be thinking about something else. DYS389 is part of the Y-STR
databsae, and YCA II is a multi-copy marker (a and b), not related to DYS389. As
far as I can recall, Relative Genetics and the Genbygen in Germany are the
only commercial companies which tests for it. Each copy has multiple alleles.
And just to be picky about nomenclature, "biallelic" usually refers to Unique
Event Polymorphisms. For example, with SNPs (Single Nucleotide
Polymorphisms), everyone has either the original base or one mutated version -- say a G
becomes a C. In theory the G could also become a T or an A, but mutations are so
rare to begin with that you're unlikely to see more than two alleles, hence
biallelic.
Ann Turner - GENEALOGY-DNA List Administrator
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