GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2004-07 > 1088913292


From: "Ken Nordtvedt" <>
Subject: Re: [DNA] Re: To SNP or not to SNP
Date: Sat, 3 Jul 2004 21:54:52 -0600
References: <dd.e6f3dc4.2e18c9f5@aol.com>


Ann, Logically what you say makes sense. But there is a curious empirical
generalization concerning just about every large-sized cluster of haplotypes
with specific STR allele frequencies. They seem to eventually go with at
least one defining SNP mutation. I'd like to hear of counter examples. As
we get to smaller and smaller breakdown of the human population, the counter
examples should eventually exist. I think my empirical generalization has
something to do with rough calculations by some that there are many, many
SNP mutations out there in the population. Almost every founder has his SNP
mutation.

I don't think SNP mutations make groups different; when we find groups that
are different people work harder to find their common and unique SNP
mutation(s).

Ken

----- Original Message -----
From: <>
To: <>
Sent: Saturday, July 03, 2004 8:48 PM
Subject: Re: [DNA] Re: To SNP or not to SNP


> In a message dated 07/03/04 12:31:32 PM Pacific Daylight Time,
> writes:
>
> > As long as I have 37 markers I am virtually certain I can tell the
> > difference between European and Asian R1a - but this probably refelcts
the fact that
> > there is as you say an as yet undiscovered SNP that is serving to ensure
that
> > these two groups are in fact different.
>
> It wouldn't require a SNP -- random factors like genetic drift,
bottlenecks,
> founder effects and so forth could explain why two groups begin to show
> different frequencies in their STR alleles.
>
> Ann Turner - GENEALOGY-DNA List Administrator
> Search or Browse the archives, Subscribe or Unsubscribe at
> http://lists.rootsweb.com/index/other/DNA/GENEALOGY-DNA.html
>
>
> ==============================
> Gain access to over two billion names including the new Immigration
> Collection with an Ancestry.com free trial. Click to learn more.
> http://www.ancestry.com/rd/redir.asp?targetid=4930&sourceid=1237
>
>


This thread: