GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2004-09 > 1094942888


From: "Joe Fox" <>
Subject: Re: [DNA] DYS 442 and 438 Blues
Date: Sat, 11 Sep 2004 15:51:22 -0700
References: <LPBBIOAAMGMFKIJPLJBCGELPDIAA.dclwilson@earthlink.net>


Russ

I had a similar problem with DYS439 at FTDNA. After several months they
decided to quit testing and just report a value of 12 - typical for the R1b
Haplogroup. When a second Fox had the same problem we concluded it was
significant and I now report a null value. Ann Turner wrote
"It is rare, but it can happen when there has been a mutation in the region
adjacent to the marker, which hinders the process used to amplify the DNA.
If
you're interested in the biology of the process, see Nancy Custer's website
on
PCR (Polymerase Chain Reaction) and primers.

http://www.contexo.info/DNA_Basics/polymerase_chain_reaction.htm

http://www.contexo.info/DNA_Basics/Primers.htm

Since the same result was obtained for two different people, you can be
confident that you're seeing a real effect, not just a laboratory error. And
since
this happens so rarely, you have an excellent means of identifying people
who
share a common ancestor. As you gather more data, you may even be able to
pin down when the mutation occurred."

Don't know if you have a similar problem with your 37 marker test. You
might query Greenspan.

Joe Fox
Lafayette, CA

----- Original Message -----
From: "David Wilson" <>
To: <>
Sent: Friday, September 10, 2004 7:30 PM
Subject: RE: [DNA] DYS 442 and 438 Blues


> Russ,
>
> Are you being tested with FTDNA? If so, have you discussed the situation
> with Bennett Greenspan or one of his technical people? (Actually, I get
the
> impression that almost everyone at FTDNA can be considered one of the
> technical people!)
>
> David Wilson
>
> -----Original Message-----
> From: Russ _ [mailto:]
> Sent: Friday, September 10, 2004 2:36 PM
> To:
> Subject: [DNA] DYS 442 and 438 Blues
>
>
> My sample has been rerun five times and the DYS 442 and DYS 438 have
> consistently "dropped out". What could be causing this?
>
> ______________________________

This thread: