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Archiver > GENEALOGY-DNA > 2004-12 > 1101994234


From: "Billy Sinor" <>
Subject: Re: [DNA] Neanderthal mtDNA
Date: Thu, 2 Dec 2004 07:30:34 -0600
References: <004c01c4d836$9a3dee00$742012ac@D71D9Y51>


Good Article
I carry 3 of the markers 6189C 16223T and 278T I always wondered what made
me so good looking
Billy Sinor
----- Original Message -----
From: "Nix Family" <>
To: <>
Sent: Thursday, December 02, 2004 12:17 AM
Subject: [DNA] Neanderthal mtDNA


> After the discussions the other day regarding the new study on Neanderthal
> genetic input into modern populations, I became a little curious as to
> what the DNA results on the Neanderthal remains actually were. I found a
> Nature article from 2000 that had a table that listed the HRV1 mutations
> for two Neanderthal skeletons. Thought I would pass them along to the list
> in case anyone is interested. Here is a link to the chart, and below is
> what I found after doing a little digging.
>
> http://www.nature.com/nature/journal/v404/n6777/fig_tab/404490a0_F2.html
>
> I did a little looking at the data. Both neanderthal skeletons showed some
> individual variations. For the time being I disregarded these, since those
> markers cannot be said to be a necessary indicator of Neanderthal ancestry
> in modern populations. After all, they weren't even shared by the two
> Neanderthals!. However, there were several HVR1 mutations that both
> Neanderthals that were tested shared in common. Since both skeletons
> shared these mutations, it would seem more likely that other neanderthals
> might also carry these same markers, and therefore pass them along if any
> interbreeding with modern humans did occur. So I will call these shared
> markers the Modal values for the Neanderthals HVR1 for lack of a better
> term. Here they are :
>
> 16129A, 16139T, 16148T, 16169T, 16183C, 16189C, 16209C, 16223T, 16230G,
> 16234T, 16244A, 16256A, 16262T, 16263.1A, 16278T, 16299G, 16311C, 16320T,
> 16362C.
>
> I compared these modal neanderthal results with the database at the
> Mitochondrial DNA Concordance. I discovered the the following mutations
> each existed in modern populations, and some are more common and
> widespread than others: 16129A, 16148T, 16169T, 16183C, 16189C, 16209C,
> 16223T, 16230G, 16234T, 16256A (very rare), 16278T, 16299G, 16311C,
> 16320T, 13262C
>
> However, some of modal Neanderthal MtDNA markers appear in no modern
> populations: 16139T, 16244A, 16262T, 16263.1A. So, it would appear that
> these four markers are uniquely Neanderthal, and if any modern person
> tested with these same four markers as the result, I would be very
> interested in seeing the other markers they also showed :)
>
>
> ==============================
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