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Archiver > GENEALOGY-DNA > 2004-12 > 1104278641


From: Doug McDonald <>
Subject: Re: [DNA] Can 385a,b = 14,15 be 15/14?
Date: Tue, 28 Dec 2004 18:04:01 -0600
References: <018d01c4ed36$9eaf6c10$6f519045@Ken1>
In-Reply-To: <018d01c4ed36$9eaf6c10$6f519045@Ken1>


Ken Nordtvedt wrote:

> I read the abstract of the Eur J Hum Gen paper Ann mentioned and got nothing much from the abstract by itself. But let me describe the importance of this question to my studies.
>
> I1a is dominated by a population of 13,14 at 385a,b. Should I try to understand its geographical distribution as a combination of two different populations --- a 13,14 population and a 14,13 population? Those would be two mutational steps apart at the marker pair 385a and 385b. The I1a 14,14 population would then be considered an intermediate state in the phylogenetic tree rather than a simple neighbor of the 13,14 population.
>

> I hope we can get this issue straightened out.


There's nothing unclear. There are two different places
where this marker, as normally measured, occurs.

Both R1a and R1b have, most commonly, one marker
at 11 and the other at 14, but they are reversed. The paper
clearly shows how they measured this. One is 11, 14
and the other 14,11.

So indeed in your purported 14,14 being "modal" you
could get to a "nominally measured" 13,14 from 14,14
in two different ways. You could get to 13,13 in
two different ways (14,14 -> 13,14 -> 13,13, and
14,14 -> 14,13 -> 13,13) etc.

And other scenarios too.

Doug McDonald

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