Archiver > GENEALOGY-DNA > 2005-01 > 1105884072

Subject: Re: [DNA] Male Line Specific Y-STR Average Mutation Rates
Date: Sun, 16 Jan 2005 09:01:23 EST

In a message dated 01/16/05 2:54:23 AM Pacific Standard Time,

> However, I suspect that
> the enzymes involved in the DNA replication process that leads to the STR
> mutation could come from the father or mother or a genetic mix of the two.
> Therefore, it seems likely that the probability of an STR mutation in any
> specific transmission event could be influenced by the mother's genes as
> well as those of the father.

I absolutely agree. The question is whether there is such a gene (or genes)
located on the Y-chromosome, so that all straight male-line descendants, even
many generations down the road, will inherit it. An autosomal (not sex-lined)
gene, whether from the father or the mother, would only have a 50% chance of
being transmitted to the next generation. As the generations pass, there's a
smaller and smaller chance that the original autosomal gene will be travelling in
the same package as the Y chromosome. Different branches of the Y-line
descendants will have picked up various versions of the DNA replicating enzymes
along the way as they marry.

Ann Turner - GENEALOGY-DNA List Administrator
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