GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2005-03 > 1109717943


From: Charles <>
Subject: Re: [DNA] mtDNA Question
Date: Tue, 01 Mar 2005 17:59:03 -0500
References: <002601c51e04$efbf20b0$6501a8c0@RJEMAIN> <4223DDB7.8060504@kerchner.com> <42248090.3060201@scs.uiuc.edu>
In-Reply-To: <42248090.3060201@scs.uiuc.edu>


Doug,

Agreed. I have updated my DNA haplotype mutation rate overview paper to
reflect a faster rate for mtDNA HVR nucleotide mutations as suggested by
Parsons work. Thanks.

Synergy at Work!

Charles Kerchner
http://www.ystrlog.org/


Doug McDonald wrote:
> A typically quoted rate for the HVR regions is one mutation
> per site per million years. At a generation time of
> 33 years this is a rate of 0.000033 per site per generation.
>
> A test of both HVRs tests roughly 1000 sites, so the
> most probable TMRCA is 15 generations, or 500 years
>
> Kerchner quotes a rate that is at the low end of what I have seen,
> roughly 1/3 what I found, so using it the TMRCA for one
> difference would be 50 generations, or 1600 years.
>
> In either case, these are "genealogical" time, not "ice-age" times.
>
> Doug McDonald


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