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From: "Angela Cone-Phipps" <>
Subject: RE: [DNA] E3a -> G2 with SNP test
Date: Sat, 23 Apr 2005 19:13:04 +0200
In-Reply-To: <042320050350.22239.4269C60A0000AAD2000056DF2200734840050B989A0E00@comcast.net>


David, All..

I may be missing something obvious here,... but - I'm not sure that this
would be the result of SNP testing errors,...

A single SNP error leading to a R or Q haplotype being misclassed as P (or
any permutation of a typing error in superhaplogroup P) might be plausible,
but E3a being mistyped as G2 would require multiple SNP test errors (given
their quite different placements in the YCC tree).

To get from E3a to G2, I assume several testing steps in a process of
elimination would have been involved. I would imagine this would have
consisted of several negative tests starting from E3a, backwards throught
the YAP clade,.. and then some positive tests forwards through the
superhaplogroup F clade presumably culiminating in positive M201 & P15
tests.

...Perhaps Leo can confirm which SNP's were tested.

I think that an odd G2 haplotype is far more likely than a series of
erroneous SNP tests.

I think this case just confirms that in some instances, we cannot reliably
infer haplogroup from haplotype.

Angela.

-----Original Message-----
From: [mailto:]
Sent: Saturday, 23 April 2005 5:51 a.m.
To:
Subject: Re: [DNA] Need some advice on E3a

I hate to be a pessimist, but if the haplotype clearly fell into the E3a
camp, but the SNP data says G2, this is a very dramatic difference and
suggests a serious error somewhere along the way. Frankly, considering the
circumstances, I think I would opt for a second opinion on the SNP - errors
can be made (vis the EDNAP study and the recent R1a "problem").

David F.



-------------- Original message --------------

> Terry,
>
> One of my participants had E3a suggested by FTDNA. SNP results came
> back as G2.
>
> Leo Baca
> Czech Regional Study
>


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