GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2005-05 > 1115238701


From:
Subject: RE: [DNA] Newbie: National Geographic, Relative Genetics, DNA
Date: Wed, 04 May 2005 20:31:41 +0000


Bill:

We will soon be in possession of the largest Scottish database ever assembled - 4000 samples to be tested to the max for every kind of Y-STR, SNP and other probes. We have the money and we have the staff, we just have to wait until all samples are analysed. One of my main goals is to shed light on the issue of Pictish survival in the Northern Isles with the arrival of the Vikings. The place name data does not bode well for a continuance of the Picts in their homeland and supports the current theory that all were put to the sword. However, preliminary work has idenfied a number of mtDNA motifs found only in Orkney and Shetland, suggesting that at least some females may have survived, and were absorbed into the Norse population. We will be tossing everything we have at the coding region to determine whether we are looking at an entirely new (unidentified) subclade of haplogroup H. And if we identify a Northern Isles Pictish Y-DNA R1b or I2 motif and associated SNP this !
would not surprise me at all. Our work should be published long before the NGS has wrapped up.

David F.



-------------- Original message --------------

> David..
>
> Perhaps the NGS project will save indigenous samples for later
> deep-level SNP testing. Recently mutated STRS are only good back to about
> 1100-1200 AD.
>
> They only way that Spencer Wells et al are going to unravel the
> ancient thread of genetic history is to perform deep level
> SNP testing..... He knows full well that STRS will only go
> back so far in time.
>
> Let us hope that the NGS project does deep level SNP testing
> and then such a statistical predictive SNP algorithm would
> not be needed.
>
> And make some major breakthrus on maternal mtDNA haplagroup "sub-clades"
> because these also need to be defined...
>
> Bill

This thread: