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From:
Subject: Re: [DNA] Middle Eastern ancestral markers on new Euro 1.0 test
Date: Fri, 27 May 2005 12:57:30 EDT


In a message dated 5/27/05 9:32:29 AM Pacific Daylight Time,
writes:

> Ann wrote:
> >The Euro test subdivides just the "European" component of the prior tests
> --
>
> The word "subdivides" is misleading here, but read on...
>
> >in other words, the four categories (Northern, Middle Eastern, Southeastern
>
> >Europe, and South Asian) will always add up to 100%, regardless of whether
> you
> >tested 50%, 75%, or 100% European on the early tests with global
> subdivisions.
>
> This statement is exactly true, but it is important to realize that
> the test can be (and assuredly has been) applied to people with 0% and
> 25% European ethinicity. The results still add up to 100%, by design.
> All humans have all of the markers used in this test, and so everybody
> will get a result. I would guess that among the 310 markers used in
> this new test there are at least a few that are also in the global
> tests, but clearly there are many additional markers.
>
> This test does not isolate just the European portion of someone's
> genome, but rather assays the whole picture.

According to their website, they only run the test if you obtain 50%+
European ancestry on version 2.5, and most of the 320 markers do not overlap the 2.5
set. (If Charles counted 310 markers, there were probably some FL -- failed or
null results -- which weren't reported.) It would certainly be interesting
to know what test results for someone with predominantly black or Native
American ancestry would look like. If they succeeded in picking markers which
mutated after migration into Europe, the "rest of the world" should be largely
homozygous for the wild allele.

Ann Turner

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