GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2005-06 > 1119905840
From: "Lowe DNA" <>
Subject: RE: [DNA] P25
Date: Mon, 27 Jun 2005 15:57:32 -0500
I know that you and Jim are really pushing the envelope here with
these new primers and sub-clade tests...and awaiting new annnouncements
from you regarding this.
Most of the men in my projects that do have matches are getting
discouraged...and then they match on YSEARCH to an entirely
For example,7 of our Stephens men matched on 37 markers to Vaughans and we
believe they might be one and the genetic lineage. They are all
generic R1b (SNP verified), but would like to go to the next sub-clade
down to see if they all match on the sub-clade SNPs...
If they match on these SNPS, then we could then say with more confidence
that the Vaughans and Stephens were probably the same genetic lineage...
So hope that you progress here spurs the other guys to think about
offering the same SNP tests to their customers.
Lord knows, STRS are revolutionary tools, but beyond a 1000 years ago
we come to a screeching halt with our projects...so SNPS offer the only
door back to the past.
As always, thanks...
From: David Faux [mailto:]
Sent: Monday, June 27, 2005 1:38 PM
Subject: RE: [DNA] P25
I can't speak for the academic community in general, but Jim and I are both
dyed in the wool genealogists with a desire to help others find their exact
place on the phylogenetic chart.
Jim is out in Shetland now swabbing all the elderly residents of Fair Isle
(his paternal ancestral home) for later Y, MtDNA and autosomal testing.
Sound familiar? The sort of activity that most of us can relate to.
However he is also a renowned geneticist who was the one who first coined
"Atlantic Modal Halotype". I would venture to say that he is cut from a
different cloth relative to many other academics - and we can all reap the
benefits. He has done all the esoteric analyses we read about in the
journal articles and has read thousands of electropherogram outputs.
It all started with our desire to create a microsatellite - based
biogeographic test since he was one of the first to publish an article on
this technology. The commercial application will take longer than
anticipated so we decided to offer SNP testing while we do the lengthy R&D
for the biogeo test. This was a direct response to the concerns expressed
on this List over the months or years and the need for someone with the
expertise necessary to step in and offer something beyond standard Y-STR,
mtDNA control region, and SNP - based biogeo tests. I am very pleased to be
in a position to assist the many people who I have met on this List (and
hope to see in DC in November). I feel quite blessed, and whether the
operation is a commercial success or not I know that along the way we can
help a lot of my fellow genetic genealogists.
-------------- Original message --------------
> Looking forward to hearing more...all of us now realize that deep SNP
> will resolve our guesstimating with these doggone STR's....
> We need the 9 or 10 major haplogroups verified down to the sub-clade with
> level SNP testing. Then we can try to connect the dots between the recent
> genealogy typified by STRs and the deep ancestry with SNPs.
> With the exception of Jim and yourself and your vigorous pursuit of these
> SNP sub-clades, where is the rest of the academics community. It appears
> are sitting back on their assets..
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