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From:
Subject: Re: [DNA] mtDNA results - Helena
Date: Fri, 1 Jul 2005 08:29:29 EDT


In a message dated 6/30/05 6:26:11 PM Pacific Daylight Time,
writes:

> Just a question: are there any mother-daughter mtDNA studies anyone knows
>
> of? Just out of curiosity? (Or multiple branch studies -- say all the
> appropriate descendants of So-and-so?)

No mother-daughter studies that I'm aware of. It wouldn't be very
cost-effective, since it would take a large number of samples to find one mutation.
However, a couple of studies have looked at deep-rooting pedigrees in Iceland and
French-Canadian populations (which both have extensive multi-generational
genealogical records).

http://www.journals.uchicago.edu/cgi-bin/resolve?AJHG991452PDF

http://www.journals.uchicago.edu/cgi-bin/resolve?AJHG013122PDF

Thomas Parsons (author of that article about using coding region mutations to
subdivide common HVR haplotypes) told me that they are readying a study on
mtDNA mutation rates. There seems to be a discrepancy between "effective"
mutation rates based on genealogical records vs phylogenetic trees (reminisicent of
the Zhivotovsky study on Y-chromosome mutation rates).


http://listsearches.rootsweb.com/cgi-bin/ifetch2?/u1/textindices/G/GENEALOGY-DNA+2004+1027821920011+F

Ann Turner

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