GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2005-07 > 1120242675


From: Robert Davenport <>
Subject: Re: [DNA] Back Mutation and Parallel Mutation
Date: Fri, 01 Jul 2005 11:31:15 -0700
References: <111.4d4beaa3.2ff6c3f2@aol.com>
In-Reply-To: <111.4d4beaa3.2ff6c3f2@aol.com>


I'd like to hear more back from the list on parallel and back mutation.

Is there a professional paper on this?








At 09:06 AM 7/1/2005, you wrote:
>Can one of you please define each of the above terms. As a layman, this is
>my understanding:
>
>Back Mutation: When it can be well documented with a paper trail that a
>particular individual has had a mutation from his father. This mutation is
>carried for a few generations, and then his descendent mutates back to the
>ORIGINAL value on the marker.
>
>Parallel Mutation: When it can be well documented with a paper trail that
>two branches of the same family have individuals who mutate, independently,
>and far distant from each other in geographic locality, to the same value on
>the same marker. In our family the mutation has occurred on DYS 437,
>probably
>from a 16 to a 17, but possibly from a 17 to a 16.
>
>On DYS 437 we have 12 persons who are a 16, compared to seven who are 17. We
>have studied in detail two of the seven families who are a 17, and noticed
>the common mutation from their immediate family, who are a 16.
>
>Please critique my understanding. Thanks!
>
>Mary Fern
>
>
>
>
>==============================
>Search the US Census Collection. Over 140 million records added in the
>last 12 months. Largest online collection in the world. Learn more:
>http://www.ancestry.com/s13965/rd.ashx

This thread: