GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2005-07 > 1120252517


From: "David M. Lawrence" <>
Subject: Re: [DNA] Back to Hammer's Paper
Date: Fri, 01 Jul 2005 17:15:17 -0400
References: <000a01c57e40$b2aa9e60$5a579045@Ken1> <42C54B9F.80601@scs.uiuc.edu> <000601c57e46$620b5ed0$5a579045@Ken1> <42C5516B.5010208@fuzzo.com> <003d01c57e51$0a4ebbf0$5a579045@Ken1> <42C56482.5000401@fuzzo.com> <004701c57e7f$75b43d60$5a579045@Ken1>
In-Reply-To: <004701c57e7f$75b43d60$5a579045@Ken1>


Yes, I've been trying to say they know which strand they are reading.
They know which direction they are reading. They know it, they know it,
they know it.

A mutation at P40 will have an effect on the complementary strand --
that's a given considering the structure of the molecule. But the
mutation always refers to strand A, not strand B.

OK?

Dave

Ken Nordtvedt wrote:
> "This is not a source of error" of what? I just today got a message from an
> academic expert in the middle of the SNP business say that a lab could read
> the complementary strands but as long as they knew what was what there would
> be no harm in the different nucelotide reading. That makes sense; but do
> all the labs know which set of strands they are measuring? In the end what
> matters to us customers without our own lab is what is reported to us.
>
> So do I believe my "T at P40" was a measurement on the same strands as
> Hammer measured "A" or do I not?
>
>
> ----- Original Message -----
> From: "David M. Lawrence" <>
> To: <>
> Sent: Friday, July 01, 2005 9:42 AM
> Subject: Re: [DNA] Back to Hammer's Paper
>
>
>
>>The DNA soup does contain strands which run both ways, but the enzymes
>>that read DNA read only ONE way. This is not a source of error.
>>
>>Dave
>>
>
>
>
>
> ==============================
> Find your ancestors in the Birth, Marriage and Death Records.
> New content added every business day. Learn more:
> http://www.ancestry.com/s13964/rd.ashx
>


--
------------------------------------------------------
David M. Lawrence | Home: (804) 559-9786
7471 Brook Way Court | Fax: (804) 559-9787
Mechanicsville, VA 23111 | Email:
USA | http: http://fuzzo.com
------------------------------------------------------

"We have met the enemy and he is us." -- Pogo

"No trespassing
4/17 of a haiku" -- Richard Brautigan

This thread: