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Archiver > GENEALOGY-DNA > 2005-09 > 1127691643


From: "Glen Todd" <>
Subject: RE: [DNA] Haplogroup mixing effect on mutation rates
Date: Sun, 25 Sep 2005 17:40:43 -0600
In-Reply-To: <000601c5c226$6e8123b0$c8129a8e@PeterAKincaid>


> With regards to the father son mutation rate studies, does
> anyone know if it has been also investigated whether
> haplogroup mixing of the parents affects the mutation rates?
> For more clarity, would more mutations be observed
> if the parents were of different haplogroups (ie. R1a
> and E3b) versus being both of the same haplogroup
> (ie. both R1b). I suspect that the assumption is that
> the mother's DNA does not have an impact. However,
> IMHO, it seems to be something worth investigating.

Peter;

Superficially this is an interesting idea, and I can see where your line of
reasoning might lead. However, in my understanding the joker in the deck
is that the Y-DNA of the mother's father simply is not expressed in the
mother at all due to the fact that women do not carry the Y chromosome, and
therefore the only possible source is the father. In other words, the
mother does not HAVE a Y-haplogroup (mt-haplogroups are totally different
things), so there's no source for 'mixing'.

Glen

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