GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2005-09 > 1127691643
From: "Glen Todd" <>
Subject: RE: [DNA] Haplogroup mixing effect on mutation rates
Date: Sun, 25 Sep 2005 17:40:43 -0600
> With regards to the father son mutation rate studies, does
> anyone know if it has been also investigated whether
> haplogroup mixing of the parents affects the mutation rates?
> For more clarity, would more mutations be observed
> if the parents were of different haplogroups (ie. R1a
> and E3b) versus being both of the same haplogroup
> (ie. both R1b). I suspect that the assumption is that
> the mother's DNA does not have an impact. However,
> IMHO, it seems to be something worth investigating.
Superficially this is an interesting idea, and I can see where your line of
reasoning might lead. However, in my understanding the joker in the deck
is that the Y-DNA of the mother's father simply is not expressed in the
mother at all due to the fact that women do not carry the Y chromosome, and
therefore the only possible source is the father. In other words, the
mother does not HAVE a Y-haplogroup (mt-haplogroups are totally different
things), so there's no source for 'mixing'.
|RE: [DNA] Haplogroup mixing effect on mutation rates by "Glen Todd" <>|