GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2005-09 > 1128125451


From: charles <>
Subject: Re: [DNA] STR mutation rates
Date: Fri, 30 Sep 2005 20:10:51 -0400
References: <1f9.1337e671.306f2a10@aol.com>
In-Reply-To: <1f9.1337e671.306f2a10@aol.com>


Ann:

At this point why can't we just collect the data. We can always decide
later which to include or not include depending on how we want to slice
and dice the data. To answer your question, I would guessimate that the
line should have at least 500 marker mutation event opportunities. But
other more talented than I may wish to offer a hard number.

I do hope you would add yours. I sent you my DNAPrint data when you were
collect that.

Charles
http://www.ystrlog.org/

wrote:
> In a message dated 09/29/05 2:00:37 PM Pacific Daylight Time,
> writes:
>
>
>>Ann wrote:
>>
>>>As for the overall rate in the log, I haven't uploaded my data, mainly
>>>because I have a rather small number of transmission events in my known
>>
>>pedigrees.
>>
>>>However, there are no mutations, and if others are behaving like me, that
>>
>>would
>>
>>>bias the log toward a higher rate.
>>
>>The obvious reply is: well, then, go ahead and upload your data.
>
>
> But... isn't the purpose of Charles' log to assemble data about *differences*
> in mutation rates between various Y-lines? A few transmission events isn't
> going to be sufficient to make any statements about that. Has anyone figured out
> how many transmission events would be required to reach a level of
> significance if say the observed mutation rate were 50% higher or lower than average?
>
> Ann Turner
>
> Ann Turner


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