GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2005-10 > 1129483425
From: Bonnie Schrack <>
Subject: Re: mtDNA haplogroups & testing . . .
Date: Sun, 16 Oct 2005 13:23:45 -0400
Ann Turner wrote:
> But back to my original plan of illustrating a way to
>check mutations, there are indeed some listed within 100bp of 4336 with
>"Proven" in the status column.
>Bottom line, I think anyone requesting mtDNA sequencing in the coding region
>should read FTDNA's disclaimer and think through various "what if?" scenarios.
A very good point, that I really should have thought of. Thanks for
pointing this out. I recommend that everyone consider this carefully
before ordering any tests of the mtDNA Coding Region. I am one of those
in the "I want to know everything" camp, but naturally many people would
not want to take on those issues at a given time, for whatever reason.
> There is a better paper for that purpose: Palanichamy et. al., Am. J.
> Human Genetics,
> 75: 966-978 (2004). It has more European subgroups, and, more
> important, includes the D-loop.
Yes, thank you Doug, I'm quite aware of that paper, and have written
about its implications for my haplogroup:
But as Anne has pointed out, there is a lot in the Kivisild paper that
you won't find anywhere else. There are other useful papers, though,
for finding out whether a given mutation site may have health
implications. Ian Logan is by far the expert on this, and I'm sure he
will soon speak up, if he hasn't already (I'm responding to the Digest).
|Re: mtDNA haplogroups & testing . . . by Bonnie Schrack <>|