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Archiver > GENEALOGY-DNA > 2005-11 > 1131767818


From: David Faux <>
Subject: Re: [DNA] Haplotype Q
Date: Fri, 11 Nov 2005 19:56:58 -0800 (PST)
In-Reply-To: <001701c5e738$c0f78940$6600a8c0@DAD>


Hello Robert:

Yes, your sample kit will be winging its way to you tomorrow.

Based on research we are doing in Orkney it may be incorrect to assume redundancy with P36 and M242. If this pans out then we have a case where NGS cannot call someone say M242 if they have tested P36+. We have already proved that this is a serious problem with someone they said was M170 based on a P19+ test and when actually tested for M170 their participant was negative on this marker. This whole area is getting grotesquely confused. Plain and simply it is wrong to test one marker and assign someone to another marker category. Either you test the marker or you don't - and if you don't it is clear that you cannot make assumptions as NGS has been doing. I guess we are playing the role of watchdog but one without teeth since they will not listen to us - or don't want to listen to us. Thus at this point, assuming your P36+ test was correct we do not know if you will be M242+ or not. Since we are in the process of testing two P36+ Q with our multiplex we shall soon have!
the
answer. If we are lucky we may even find that you belong to one of the Q subgroups that have been identified. We will then genotype my two Shetland Q with direct sequencing and see if their haplogroup status is the same as yours.

David Faux.

Robert Paine <> wrote:
David I am an English "Q" P36+ M3- I have ordered the Ethnoancestry Y -
Haplogroup Multiplex Y-SNP Test. I hope to find if I am M242 (plus or
minus). The Genographic project assigned me M242, based on my tested P36+
result without actually testing for M242

R Paine


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