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Archiver > GENEALOGY-DNA > 2005-12 > 1135087845


From: "David Wilson" <>
Subject: Re: [DNA] Ethnoancestry Offers YSTR18 Haplotype Test
Date: Tue, 20 Dec 2005 06:10:45 -0800


Roxanne,

Just one point about differentiation: while one will always learn something
from a panel of SNP tests, that doesn't mean you will always have an
informative positive result in the package. Sometimes (as in my case so
far), all the downstream SNPs will come back negative. That leaves me in
haplogroup R1b1c* (or R1b3*, as we are using unofficial and official
nomenclature systems simultaneously these days; whatever label you put on
it, I am M269+).

But remember that other people are getting SNP tests too. As some of them
test positive on this SNP or that one, they and their kin are moved out of
the undifferentiated collection. Today the R1b1c* clade is about 20 - 25%
smaller than it was just six months ago, largely as a result of the new SNP
tests offered by EthnoAncestry. As new SNPs are developed and people are
tested for them, the "remainder" subclade becomes better defined by default.

But I think there is a larger question you posed. If you are looking for
matches to help with family history or finding possible kin among
individuals with differing surnames, then you are better off ordering
additional STRs than SNP refinements.

There is a Pendleton haplotype in Ysearch (2YEUW), but that haplotype is
unambiguously I1a. I take it this haplotype would reflect your paternal
ancestry and is not your husband's results. Is his haplotype on Ysearch? I'd
be happy to take a look at it and tell you if anything jumps to my eye. You
say his haplotype is modal at "almost every marker." But there may be
something to be said about the ones where he differs.

David Wilson
Wilson Surname Project Co-Administrator



On 12/19/2005 10:35:54 AM, Robert Stafford () wrote:
> A lot of R1bs only differ by a few markers from the modal. However, in
> combination with the surname, 37 markers is more than sufficent. Unless
> you have reason to believe that there is a false paternity, you
> don't need to concern yourself with matches with other surnames.
>
> If he has a documented genealogy with gaps, it is possible that a
fortuitous mutation might show up to tag his branch. However, this is really
hit or miss and is expensive. I recommend this approach only after intitial
deep testing of genealogies, so there will be enough donors to isolate the
mutation.
>
> Bob Stafford
>
> Roxanne Pendleton <> wrote:
> Perhaps you can give me some direction. I had my husband's
> DNA run for 37
> markers and found he is an Rb1 (M343). At almost every marker his result
> is the same as the highest percentile of Rb1 people. Nothing at all
> remarkable. Nothing. What if any, snps should I run to differentiate him
> from the herd? Should I do additional markers or snps? Curious.
>
>
> >From: David Faux
> >Reply-To:
> >To:
> >Subject: Re: [DNA] Ethnoancestry Offers YSTR18 Haplotype Test
> >Date: Sat, 17 Dec 2005 0

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