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Archiver > GENEALOGY-DNA > 2006-01 > 1136574876


From: Thomas Krahn <>
Subject: Re: [DNA] YCA iib mutations: infinite alleal
Date: Fri, 06 Jan 2006 20:14:36 +0100
References: <25b.4b18521.30eedd91@aol.com> <007101c612ef$a0430bb0$32a28843@yourxhtr8hvc4p>
In-Reply-To: <007101c612ef$a0430bb0$32a28843@yourxhtr8hvc4p>


jimbettyd wrote:

>
>> writes:
>>
>> Has anyone else seen an apparent single jump from 19 24 or 19 23 to
>> 19 19?
>>
>>
> Yes, my YCAII went from 19,23 to 19,19, apparently fairly recently.
> My haplotype is close to a typical R1b, but has several unusual values
> that puts it at about 35 on Whit's estimator with Q close behind. I
> am WHVZW in Ysearch.
>
> Jim Davidson

Always have in mind, that you're coping with a duplicated marker that is
located on the arms of a palindrome.
Those examples above are crying for the existence of a recombinational
loss of heterozygosity (recLOH).
See:
http://www.dna-fingerprint.com/modules.php?op=modload&name=Sections&file=index&req=viewarticle&artid=9

Thomas

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