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Archiver > GENEALOGY-DNA > 2006-01 > 1137037306


From: "Dennis Wright" <>
Subject: RE: [DNA] DYS385 hi - lo?
Date: Thu, 12 Jan 2006 14:41:46 +1100
In-Reply-To: <NFBBJIGLNLMGJIOLOGFBKEKJGDAA.scorpion@netconnect.com.au>


Hi John,

I have just had a read of the Kittler article and 99% is way over my head
but I did pull out this, which I quote:-

"When analysed simultaneously, the convention for statistical analyses of
DYS385 data is that the shorter allele is artificially assigned to DYS385a
and the longer allele to DYS385b. Thus, for hg3 Y chromosomes, with high
frequency of DYS385a-11 and DYS385b-14 (and their derivatives), this
approach would reflect the true alleleĀ–locus assignment, and in general the
higher the frequency of hg3 chromosomes in a population, the lower the
misclassification rate. In contrast, for hg1 Y chromosomes, with high
frequencies of DYS385a-14 and DYS385b- 11 (and their derivatives), this
approach would not reflect the true alleleĀ–locus assignment, and the higher
the frequency of hg1 chromosomes in a population, the higher the
misclassification rate."

When I look at the suggested ancestral haplotypes for hg1 and hg3, I find I
am closer to hg1 ie Spanish, than hg1 ie East European with the exception of
my 11:14 at DYS385. Perhaps I am truly 14:11 and have been incorrectly
assigned.

Dennis in Oz


> Further to this point, I thought for R1b the modal values were:-
> DYS385a =11 90%
> DYS385b= 14 52%, =15 20%
> In this basis, most R1b would be "lo-hi" or am I missing
> something? Is this
> only the SWAMH of R1b?
> Dennis in Oz
>
> > Hi Nelda and John,
> >
> > My markers are the same as yours, DYS385a = 11 and DYS385b = 14
> and I ask
> > the same question, am I lo-hi ?
> > Dennis in Oz
> >
> > >
> > > John,
> > > Question hi - lo/ lo- hi for DYS 385,
> > > So if I have DYS385a = 11 and DYS385b = 14, is that a lo - hi?
> > >
> > > Still learning, so what (Briefly) does that tell me, other then
> > it is not
> > > the norm for R1b?
> > >
> > > Nelda

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