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Archiver > GENEALOGY-DNA > 2006-02 > 1139685172


From: Robert Stafford <>
Subject: Re: [DNA] Different Values Just at DYS389i & DYS389ii
Date: Sat, 11 Feb 2006 11:12:52 -0800 (PST)
In-Reply-To: <00d601c62f34$7c8f0370$6500a8c0@am.trimblecorp.net>


Bill,

There is nothing unusual about DYS389, except the way the matches are determined for DYS389ii, as noted in Ken's post.

A mismatch on one marker indicates that you are closely related, but DNA can't pin it down the exact relationship any more than that. A mismatch on one of 43 markers, even against the ancestral haplotype, is pretty common. Two mismatches against the ancestral is not unusual.

You will want to test a descendant of another son to determine which is the ancestral value and then make all comparisons against it. However, it might also be determined if another from your branch matches the other person or vice versa.

Absent the paper trail, you could be brothers or very distant cousins. All you can really say is that the test didn't disprove the paper trail, i.e., it is consistent with it. The only exception would be a fortuitous mutation that defines a branch. Even then, as our discussions on parallel mutations indicate, it is necessary to weigh in the paper trail.

DNA is really only conclusive when it shows that people are not related. If that happens, it is necessary to test other branches to eliminate the possibility of a false paternity (adoption, infidelity, etc.) between the progenitor and the donor. Sometimes, the results are in a gray area, requiring additional testing to look at the pattern of mutations.

Bob Stafford



billdenney <> wrote:
As a newbie, we've just received our Y-DNA test results for our first two people to be tested (who share a common ancestor, b ca 1722). On a 43-marker test, we match perfectly on all but two markers (DYS389i and DYS389ii). Is there any significance in the fact that we disagree on just those two markers?

Customer Code DYS19 DYS385a DYS385b DYS388 DYS389i DYS389ii DYS390
KBG715 14 11 14 12 14 30 24
23GJE8 14 11 14 12 13 29 24

Can we say with confidence that for the two of us, we've proved our paper trail back to this common ancestor, b ca 1722? We descend from two different sons of his, per our pedigree charts.

Any comments would be much appreciated. Thanks.

Bill Denney
Denny DNA Surname Administrator


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