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From:
Subject: Re: [DNA] More on C4 aka DYS635 Behavior in I1a
Date: Sun, 30 Apr 2006 11:25:33 EDT


In a message dated 04/30/06 6:58:23 AM Pacific Daylight Time,
writes:

> I mentioned in my first message that some other haplogroups including J and
> N showed the similar sudden collapse of haplotype count as one moved from 21
> to 20 repeats. But some haplogroups simply have different modal values.
> R1b, for instance, is normally 23, with some varieties being modal 24 and
> even 25 R1a is normally 23. G is modal 20
>
> But the 23 to 22 barrier seems comparably difficult to penetrate going down,
> just as the 21 to 20 barrier seemed for I1a. Look at these different R1b
> and R1a populations

It might be interesting to actually sequence C4 in a few samples from the
various haplogroups to see how stable the internal structure is, with the
alternating short TATC/TATG repeats. In theory, the last section with 10 repeats
would be the most likely to mutate, and it's a bit on the short side itself.

(TATC)3 (TATG)2 (TATC)2 (TATG)2 (TATC)2 (TATG)2 (TATC)10

Ann Turner


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