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Archiver > GENEALOGY-DNA > 2006-06 > 1150315024


From: John Lerch <>
Subject: Re: [DNA] 5 mystery markers
Date: Wed, 14 Jun 2006 14:57:04 -0500


I apologize if you noticed your error Ken,
If you exclude 5 markers the number of possible such sets is
43*42*41*40*39. which is about 10^5 *4*5 or 10^8--large but not
astronomical.
Ken wrote
From: "Earl Beaty" <>

A suspicion is that Sorenson knows something about these markers

> which caused them to pass. The 5 suspect markers are: 607, 576, 570, CDYa,
> CDYb. We find that if we simply ignore the suspect 5, the conclusions are
> changed significantly. It is not good that the conclusions should
> depend so
> much on which company was chosen.


{{{ Do you recalibrate your average mutation rate and number of markers
when you exclude those 5? Of course there is the absurd extreme which I
believe no one actually does, but illustrates the dangers of excluding
markers. Suppose I kept excluding different sets of 5 markers out of my
43, and for each different exclusion (an astronomical number exist)......

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