GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2006-06 > 1150659356
From: (John Chandler)
Subject: Re: [DNA] PubMed abstract: DAZ genes on the Y chromosome
Date: Sun, 18 Jun 2006 15:35:56 -0400 (EDT)
In-Reply-To: <firstname.lastname@example.org> (DNACousins@aol.com)
Fernandes AT, Fernandes S, Goncalves R, Sa R, Costa P, Rosa A, Ferras C,
Sousa M, Brehm A, Barros A. wrote:
> and our data show that the DAZ gene is not under
> selective constraints and its evolution depends only on the mutation rate.
I find that statement puzzling. The only way they could make that
claim is to show either that there is no difference in the apparent
rates for synonymous and non-synonymous mutations within the gene,
or that the apparent rate within the gene is the same as the rate
for the chomosome as a whole. Neither method seems indicated by
anything else mentioned in the abstract. Also, I find the claim
hard to believe, whatever method they used to come to it.