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Archiver > GENEALOGY-DNA > 2006-08 > 1154461116


From:
Subject: Re: [DNA] Sorenson mtDNA search engine bug
Date: Tue, 1 Aug 2006 15:38:36 EDT


In a message dated 8/1/2006 10:55:35 AM Pacific Daylight Time,
writes:

> There's a minor bug in the Sorenson search engine (it has a workaround).
> It seems that when the search engine encounters a site with multiple
> mutations, it treats them as all being part of the required search.
> IOW when we search for 524.1A, you can't just search for no
> variants--you have to have at least one difference to allow for 524.2C.
> So to be specific when I searched on 499A and 524.1A, if I made the
> allowed number of differences be zero, I get a sorry message. IfOTOH
> one allows for one or 2 differences, one gets one difference hits on
> BOTH 499A,524.1A and 499A,524.2C even though one didn't set 524.2C as a
> search parameter.
> JAL
>

In this particular case, it's best to enter both 524.1A and 524.2C as part of
your search strategy. That region has several sets of "AC" in a row, and
mutations (insertions and deletions of the "AC" motif) in that region almost
always come in pairs. In fact, I can't recall off-hand seeing one without the
other, although it's theoretically possible, like partial repeats in Y STR markers.

Ann Turner

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