Archiver > GENEALOGY-DNA > 2006-08 > 1157045233

From: "Alfred A. Aburto Jr." <>
Subject: Re: [GENEALOGY-DNA] can we do better for genetic distance?
Date: Thu, 31 Aug 2006 10:27:13 -0700
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In-Reply-To: <>

TMRCA will work.
For 50% probability 10/12 indicates 61 generations to TMRCA.
For 50% probability 65/67 indicates 10 generations to TMRCA.

> Rick Arnold wrote:

>Why should 10/12 matches and 65/67 matches both be designated GD=2? Is there a better convention out there? Perhaps the use of proportion or percentage match or mismatch could provide a more precise index of genetic distance. So a 10/12 match would be an 83% match while a 65/67 match would be a 97% match (or respectively 17% and 3% mismatches). I'm sure there could be something even better than this suggestion, perhaps weighting the value to account for individual marker mutation rates. But in any event it seems the standard use of GD in unnecessarily crude. Often I have seen posters here and elsewhere refer to a GD value without reference to the number of markers compared. Isn't there something better?

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