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Subject: [DNA] PubMed abstract: autosomal markers in the Basque
Date: Wed, 6 Sep 2006 13:48:51 EDT
Most if not all of the "genetic systems" listed in this abstract were studied
by Luigi Cavalli-Sforza in "History and Geography of Human Genes." As far as
I know, there is no particular significance to the genetic systems, other than
they have been observed to vary in different populations. This article comes
down on the side of some present-day Basques being representative of the
ancient ones.
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Anthropol Anz. 2006 Jun;64(2):173-87.
Genetic polymorphisms in autochthonous Basques from northern Navarre.
Calderon R, Perez-Miranda AM, Fuciarelli M, Scano G, Carrion M,
Alfonso-Sanchez MA, Pena JA, Ambrosio B, De Stefano G.
Departamento de Zoologia y Antropologia Fisica, Universidad Complutense de
Madrid, Madrid, Spain.
This survey reports primary results of classical allele frequencies on ten
protein loci in a Basque population sample from northern Navarre, the less known
from an anthropological and genetic point of view than the populations of the
other Basque territories of Spain. Since ancient times this has been a zone
of Basque population settlement, and the Basque language (Euskera) still
remains deeply rooted among its autochthonous population. A total of 122 blood
samples from unrelated northern Navarrese with autochthonous ascendants to the
third generation were typed for GC, HP, PI, TF, ACP1, AK1, CA2, ESD, PGD and PGM1
genetic systems. Basque surnames and birthplaces were the criteria used to
define family origins. Genetic structure was analyzed on different population
hierarchical levels. Northern Navarre seems to be the most genetically deviated
area in comparison with other Basque groups. The highest level of
differentiation is observed between Navarrese and Alava Basques whereas Guipuzcoa province,
the territory adjacent to northern Navarre, presents the lowest genetic
distance from the study area. Northern Navarrese show some distinguishing genetic
characteristics in relation to other Basque relative samples, which include
high frequencies for PI*M1 and TF*C1 and low levels of PGD*C and PGM1*2 alleles.
When the genetic data reported here are analyzed jointly with GM allotypes
frequencies, the results significantly reinforce the relative position of
Navarrese Basques as well as the topology of the Basque cluster on genetic maps. The
analysis of relationships among the genetic structures of Basque population
samples leads us to ask ourselves which of them fits in best with the ancient
Basque population. Classical geographers placed the tribe of the Vascones in the
geographical region currently known as Navarre, so extant Navarrese Basques
might be considered firm candidates to denote the anthropological and genomic
distinctiveness of the ancient Basques.
PMID: 16850769 [PubMed - indexed for MEDLINE]
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