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Archiver > GENEALOGY-DNA > 2006-12 > 1166416238


From: "Ken Nordtvedt" <>
Subject: Re: [DNA] UEP Mutation
Date: Sun, 17 Dec 2006 21:30:38 -0700
References: <000c01c7225c$a655e090$6d4c2b3f@DW>


There seem to be fourteen DYS385 = 9-14 R1b haplotypes in SMGF out of more
than 3000. No 9-13 ones.

Ken

----- Original Message -----
From: "David Wilson" <>
To: <>
Sent: Sunday, December 17, 2006 9:26 PM
Subject: Re: [DNA] UEP Mutation


> If 385 is 9-13, that rare combination speaks so loudly to me that other
> differences sort of fade into the background. I would consider the two men
> related and probably sharing a recent common ancestor.
>
> I should correct one thing I said. I read right past the c and g
> distinctions in your first post. Now that I am paying attention to them,
> it
> seems to me a RecLOH is not possible. There is a one-step difference in
> the
> g-type allele, while the three c-type alleles remain unchanged. If I
> understand the process, a RecLOH would have wiped out the g-type allele
> completely, leaving a c-c-c-c pattern to the 464 copies.
>
> I found the two haplotypes you are comparing in Ysearch, as well as a
> handful of other R1b1c7 types with 9-13 at 385. There is wide variation in
> the surnames, and I wonder if this is a subcluster. Until tonight I had
> come
> across only one such haplotype in my travels, and I had considered it a
> rare
> outlier. I need to look into this.
>
> David Wilson
>
>
>
> -----Original Message-----
> From:
> [mailto:] On Behalf Of John Megonnigil
> Sent: Sunday, December 17, 2006 7:45 PM
> To:
> Subject: Re: [DNA] UEP Mutation
>
> David
>
> Hmmm. I thought that a change in the c-g etc was a UEP event by itself?
> Since I seem to have that thought wrong, what would be an example? There
> is
> only what appears to be -3 or -1 with a reLOH event. The surnames are NOT
> known to be related, however from the same general time and area.
> Only differences at Y37 are
> DYS458=18
> CDY=39-39
> CDY464=15-15-17-17
>
> DYS458=17
> CDY=38-39
> CDY464=15-16-16-17
>
> they both even match with a rare CDY385 with 9-13
>
> --
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> 3:17 PM
>
>
>
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