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Archiver > GENEALOGY-DNA > 2007-01 > 1167751000


From: "Alfred A. Aburto Jr." <>
Subject: Re: [DNA] DYS388 mutation rate
Date: Tue, 02 Jan 2007 07:16:40 -0800
References: <bd2.c5ee536.32c90b09@aol.com> <4597D720.7040707@sbcglobal.net> <000801c72cfe$3bdbe2d0$6400a8c0@Ken1> <REME20061231152748@alum.mit.edu><REME20070101155902@alum.mit.edu> <4599F63F.4020206@mchsi.com>
In-Reply-To: <4599F63F.4020206@mchsi.com>


If John ran his algorithms using Y-STR modal values by haplogroup then
perhaps that would give the required resolution, provided sufficient
data samples exist. For example DYS388=16 is modal for J1, DYS388=15 is
modal for J2, DYS388=14 is modal for haplogroup ?, DYS388=13 is modal
for haplogroup ?, DYS388=12 is modal for R1b, ..., etc. From the
mutation rates for these one perhaps could develop a curve of mutation
rate versus repeat length (modal value) for a given Y-STR locus. Just
thinking "out loud" here. The lowest repeat length (haplogroup modal
value) would correspond to the slowest mutation rate while the highest
repeat length (modal value) would correspond to the fastest mutation rate.

Humm, it may be that the haplogroup with the overall (for all markers)
lowest modal values would be the oldest haplogroup? One could test this
I suppose using the ISOGG Y-DNA tree and the haplogroup modal values ...
still thinking "out loud" here ....
Al

PS: I removed the "was" part from the subject ... and took out the extra
"DYS" ...

> Rebekah wrote:

>That is an interesting histogram. What needs to be done to show that the
>rate change is at 388(>=12) and not to 388(>=14)?
>
>John Chandler wrote:
>
>
>>Another table that might be of some interest: the histograms for the
>>two subsets:
>>
>>388 ( 4-12)= 1 0 0 1 1 1 61 29 6190
>>388 (13-18)= 761 925 287 144 28 1
>>
>>

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