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Archiver > GENEALOGY-DNA > 2007-03 > 1174654182


From: "William Hurst" <>
Subject: Re: [DNA] mtDNA of H in Native American
Date: Fri, 23 Mar 2007 08:49:42 -0400
In-Reply-To: <679963.92884.qm@web59213.mail.re1.yahoo.com>


Hi Cheryl and all,

>In short, mtDNA is still a mess, because researchers are still attempting
>to
>pretend that mitochondrial mutations are UEPs, when they obviously are not.

The HVR2 mutations you listed, such as 146C, 195C, etc., are certainly not
UEPs. However, in K, 497T, which defines K1a, is about as close as you can
get to one. I found one on MitoSearch in hg U, but I think it's really a K.
Also, 498-, which defines K1c, apparently has only been found otherwise in
L0.

Others, such as 16048A, are rarely found in other haplogroups; so when it
occurs in K, I put the haplotype in my proposed subclade K1a10. I think a
good rule is that the more haplogroups in which a mutation is found, the
less useful it is in defiining subclades within a haplogroup. Conversely,
the fewer haplogroups in which a mutation is found, the more useful it is in
the haplogroups in which it is found. Ron Scott's downloads from MitoSearch
are very useful for looking up the mutations. I wish he would compile the
HVR2 mutation information as he did for HVR1. Hi Ron.

Bill Hurst


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