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Archiver > GENEALOGY-DNA > 2007-05 > 1178626583


From: Vincent Vizachero <>
Subject: Re: [DNA] Possible reporting error on SMGF - DYS463=19
Date: Tue, 8 May 2007 07:16:23 -0500
References: <BFECJOAEEPCFBFFLLBGPIEBNDBAA.scorpion@netconnect.com.au>
In-Reply-To: <BFECJOAEEPCFBFFLLBGPIEBNDBAA.scorpion@netconnect.com.au>


On May 8, 2007, at 1:36 AM, Dennis Wright wrote:

> I do accept the principal of mutation but this marker is extremely
> robust
> within this cluster, almost to the point where I am suggesting it as a
> 'Mini-SNP" to prove or disprove 'outliers'.

I agree with Jim. DYS463 does not appear to have a particularly low
mutation rate, so if you look at enough haplotypes you are bound to
find exceptions to the rule.

Just as a matter of principle, we must be careful to avoid
circularity of reasoning when building haplotype clusters
(especially ones that are likely to be proxies for genuine
subclades). You should not use DYS463=23 to help define Irish Type
III and then claim that all Irish Type III has DYS463=23.

Vince

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