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Archiver > GENEALOGY-DNA > 2007-07 > 1183301552


From:
Subject: Re: [DNA] Help please with marker 458
Date: Sun, 1 Jul 2007 10:52:32 EDT


In a message dated 7/1/2007 5:14:09 AM Pacific Daylight Time,
writes:

> I can't say that I know exactly what the relationship between the
> mutation rate and diversity is, so I'm very interested to see if
> somehow John Chandler's method can disentangle the data. Generally I'd
> expect that the higher the mutation rate, the more spread there'd be
> *on average* in the STR histogram for a marker, but that wouldn't
> necessarily be the case due to random genetic drift.

For some empirical data, Leo Little once calculated the correlation between
gene diversity and mutation rate, using "Marker Details" from SMGF:

http://www.smgf.org/ychromosome/marker_details.jspx

There was a correlation, but not perfect:

http://archiver.rootsweb.com/th/read/genealogy-dna/2006-02/1139690518

Ann Turner


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