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Archiver > GENEALOGY-DNA > 2007-07 > 1183305675


From: "Ken Nordtvedt" <>
Subject: [DNA] Fw: Help please with marker 458
Date: Sun, 1 Jul 2007 10:01:15 -0600


> Underlying sub-clade structure will create unpredictable noise in the gene
> diversity; it won't necessarily lower it. It depends on the modal jumps
> between the various clade founders.
>
> Look at your DYS455 row of diversities, for example. DYS455 is a very
> slow mutator, so its diversity should be low which it is except for
> hapalogroup I which you mentioned you did not break down into its clades.
>
> We know I1a is 8 at DYS455, I1b2* is 10 at 455, and everything else in
> hapalogroup I is 11 at DYS455. Hence the diversity measure used gives a
> huge value for haplogroup I taken as a whole. This is due to the
> diversity of 455 among the relatively few founders which is statistically
> a inherently noisy thing.
>
> Ken
>
>
>
> ----- Original Message -----
> From: "Leo W. Little" <>
> To: <>
> Sent: Sunday, July 01, 2007 9:36 AM
> Subject: Re: [DNA] Help please with marker 458
>
>
>> In response to Ken's comments,
>>
>> I removed near-matching haplotypes within surname groups before compiling
>> the statistics on the
>> two web pages listed below.
>>
>> However, any underlying sub-clade structure will still lower the gene
>> diversity (GD).
>>
>> ... and my apologies to Ken for not breaking out HG I any further.
>>
>> ---------------------------------------------------------------------------------
>>
>> Leo W. Little wrote:
>>
>> See http://freepages.genealogy.rootsweb.com/~geneticgenealogy/67GD.htm
>> for gene diversity per
>> marker of five haplogroups based on 67-marker haplotypes.
>>
>> See http://freepages.genealogy.rootsweb.com/~geneticgenealogy/yfreq.htm
>> for the number of samples
>> for each haplogroup and marker.
>>
>> The correlations between gene diversity and the Chandler rates for the
>> first 37 markers are:
>>
>> E3b, 0.56
>> I, 0.49
>> J2, 0.48
>> R1a, 0.55
>> R1b, 0.66
>>
>> -------------------------------------------------------------------------
>>
>> wrote:
>>
>> Leo Little once calculated the correlation between gene diversity and
>> mutation rate
>>
>>
>>
>



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