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Archiver > GENEALOGY-DNA > 2007-07 > 1184440783


From: "Elizabeth O'Donoghue" <>
Subject: Re: [DNA] Bottlenecks - R1b1c7 as a calibration tool-The"final"version
Date: Sat, 14 Jul 2007 20:20:06 +0100
In-Reply-To: <3b2a446a0707141130q183c4272idd907eb9ca1457d1@mail.gmail.com>


On 7/13/07, Elizabeth O'Donoghue <> wrote:

> Sasson - smaller than what?

smaller than observed mutation rate - this is so-called "fudge factor"

>> They found that under assumption of "constant total population size"
>> the simulations do show "the accumulated variance is on average
>> 3-to-4 times smaller".

-------

So does that mean that if the observed mutation rate is 0.002, for instance,
then the simulation indicated that it was actually 3-4 time *less* frequent
than the observed rate, or only about 0.0005-6? Meaning that the TMRCA
would be 3-4 times *more* recent than calculating with the observed rates?
I thought it was the other way round - that the fudge factor would length
the time to MRCA. Please clarify for a confused mind.

Thanks. Elizabeth



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