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Archiver > GENEALOGY-DNA > 2007-07 > 1185819887


From:
Subject: Re: [DNA] difference in mutation rates
Date: Mon, 30 Jul 2007 14:24:47 EDT


In a message dated 7/30/2007 9:13:06 AM Pacific Daylight Time,
writes:

> First question is there a list on mutation rates of all 67 markers, and is
> there a concensus in the acedemic field on the differing rates.
>
> The issue is important in the sence that a 1 difference in a slow mutating
> marker is more troubelsome for geneologic research that changes in faster
> mutatiing markers. The genetic distances measured in just discrete ones
> does not recognise this. If a concensus can be acieved in average mutation
> rates per marker a new appoach on measuring differences can be achieved.

There's not really enough data yet to estimate mutation rates for individual
markers in the last set of 30. For markers 1-37, see John Chandler's article
in the Journal of Genetic Genealogy (JoGG)

http://www.jogg.info/22/Chandler.pdf

But surprisingly, the individual rates don't matter all that much for
estimating the time to the Most Recent Common Ancestor (MRCA). It's the average rate
that's more important. Also, if one pair matches each other on 66/67 markers
(with the difference on a fast-moving marker) and a different pair matches each
other on 66/67 markers (with the difference on a slow-moving marker), the
time to the MRCA is actually shorter if the marker is slow-moving. However, the
difference is very slight and makes no practical difference. Here's an old
message where I gave some concrete examples:

http://archiver.rootsweb.com/th/read/genealogy-dna/2005-09/1127430282

Ann Turner



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