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Archiver > GENEALOGY-DNA > 2007-08 > 1186195886


From:
Subject: Re: [DNA] mtDNA H2a phylogeny
Date: Fri, 3 Aug 2007 22:51:26 EDT


>Kathy, can you please give me the complete
>reference on this Helgason and Sykes paper?

>And how do I find this sequence at Genbank?


Helgason paper:
_http://www.journals.uchicago.edu/AJHG/journal/issues/v68n3/002146/002146.html
_
(http://www.journals.uchicago.edu/AJHG/journal/issues/v68n3/002146/002146.html)
Keep in mind that this paper does not mention H2 at all even though
there are sub-clusters that we would put in this category today. The
Oxford scientists were not using the same phylogeny in 2001.

Go to:
_http://www.ncbi.nlm.nih.gov/BLAST/_ (http://www.ncbi.nlm.nih.gov/BLAST/)
Choose Nucleotide Blast
Enter Accession number A4025540
Nucleotide collection (nr/nt)

The matching H2a2 FGS sequence will have the alignment
off by one number from the CRS. All the SCOT
sequences are from Helgason's paper but will only
report the HVR1 results so the coding region
suspected 3388 polymorphism will not be present.
I am assuming these would fit into H2a2 today
because four markers would not occur together
like this by chance alone:
16235 + 16291 + 16293 + 16400

It takes a lot of detective work to find the connections.

Kathy J.



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