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Archiver > GENEALOGY-DNA > 2007-11 > 1194004812


From:
Subject: Re: [DNA] Sorenson and SNPs
Date: Fri, 2 Nov 2007 08:00:12 EDT


In a message dated 11/1/2007 9:18:44 PM Pacific Daylight Time,
writes:

> Does anyone know whether Sorenson SNPs their samples or if they
> predict/infer haplogroup, or some combination of both?

When you say Sorenson in this context, I assume you mean Sorenson Molecular
Genealogy Foundation (SMGF, the research project), not Sorenson Genomics (the
testing facility, which can do any type of testing to order):

http://sorensongenomics.com/dna_analysis.html

The mtDNA haplogroup prediction (and it is a prediction) is an added feature
of the GeneTree site. SMGF itself has no particular need for haplogroup
information for its research goals, since it is using haplotypes in conjunction with
genealogical information. Of course, haplotypes are much more informative
than haplogroups for that purpose. There are probably hundreds if not thousands
of distinct haplotypes within haplogroup H, for example.

SMGF did do some validation studies with SNPs to develop the prediction
algorithm for GeneTree. I suspect the success rate would be comparable to the
findings of the Genographic Project, where motifs for some haplogroups are quite
reliable and others are a bit fuzzier.

Ann Turner




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