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Archiver > GENEALOGY-DNA > 2007-11 > 1195455028


From: OrinWells <>
Subject: Re: [DNA] Odd DYS464 results
Date: Sun, 18 Nov 2007 22:50:28 -0800
References: <8E9835FF-3E2B-4064-AB5E-FC0783C88832@vizachero.com><BFECJOAEEPCFBFFLLBGPIEIOEBAA.scorpion@netconnect.com.au>
In-Reply-To: <BFECJOAEEPCFBFFLLBGPIEIOEBAA.scorpion@netconnect.com.au>


Hmmm. This is interesting. We recently ALSO had a sample returned
with only 3 DYS464 values. This particular test was a surprise
because it didn't match the haplotype we expected and I overlooked
that fact there were 3 peaks instead of four. Now I see we also had
another not long ago with the same curious 3 peaks. ALL other tests
we have run through Relative Genetics have had at least 4 peaks (we
did have two with 6 peaks).

As you know DNAHeritage runs their tests through Sorenson Genomics as
does Relative Genetics. This sounds like something we need to push a
little on.

At 09:25 PM 11/18/2007, Dennis Wright wrote:
>Yes, I should have picked this up myself. I was just repeating DNA
>Heritage's explanation.
>We have requested, and DNA Heritage have promised to supply a scan of the
>electropherogram ... lets see what it shows.
>I had suggested a retest with another lab, and that is still a backup
>position.
>
>Dennis W
>
>****************************************************************************
>~
>~I may be dense, but if there were three peaks then why are there only
>~two values? Normally, three peaks should lead to three different
>~alleles (e.g. 11,13,13,15 or 11,11,13,13,15,15). not just two. In
>~other words, there should be one large peak for 11, one large peak
>~for 13, and one large peak for ??.
>~
>~This strikes me as an odd result, and one that might justify being
>~checked by another lab who uses different primers. It is this kind
>~of situation in which FTDNA's DYS464X test can be invaluable, though
>~of course the expense of switching testing to a different lab is not
>~negligible.
>~
>~Vince
>~
>~
>~
>~reported, that should show up as one double height peak
>~On Nov 18, 2007, at 3:41 AM, Dennis Wright wrote:
>~
>~> All that is missing is DYS464=13,13,15,17. He has tested at
>~> DNAHeritage
>~> DYS464=11,13,13,-. When a retest was requested, Alistair Greenshields
>~> advised there were only three large peaks and perhaps the marker
>~> should be
>~> read:-DYS464=11,11,13,13,13,13. We are not altogether happy with this
>~> explanation.
>~> What do others think?
>~
>~
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Orin R. Wells
Wells Family Research Association
P. O. Box 5427
Kent, Washington 98064-5427
<>
http://www.wells.org
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