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Archiver > GENEALOGY-DNA > 2007-12 > 1199052847


From: charles <>
Subject: Re: [DNA] Chances for Finding Clade-separating SNP
Date: Sun, 30 Dec 2007 17:14:07 -0500
References: <003e01c84b1e$76c47df0$6400a8c0@Ken1> <11985d4c0712301216u4750d8b2g1017bc7702a07820@mail.gmail.com> <004b01c84b23$f130b9a0$6400a8c0@Ken1><47780489.1020004@kerchner.com><11985d4c0712301302p6e166d41veaa32bd94ca48b70@mail.gmail.com>
In-Reply-To: <11985d4c0712301302p6e166d41veaa32bd94ca48b70@mail.gmail.com>


Rebekah,

Yes.

Charles


Rebekah Canada wrote:
> Charles,
>
> Is that a per nucleotide per generation mutation rate?
>
> The thing is that to the best of my knowledge nobody has ever done a
> father/son mutation rate study for ySNPs.
>
> On Dec 30, 2007 2:50 PM, charles <> wrote:
>> Ken,
>>
>> I don't know where that number you cite is from but here is one that I use and
>> the source:
>>
>> "Reference Y-DNA nuclear molecule (paternal line nuclear DNA - located inside
>> the cell nucleus) nucleotide (SNP) mutation rate:
>> 2 x 10^-8 or 0.00000002 per nucleotide transmission event (birth of a new
>> generation) is a commonly used value. The 0.00000002 one significant digit
>> average mutation rate I'm using is this overview was given in a presentation
>> given in February, 2003 to the Department of Biological Sciences at George
>> Washington University by Dr. Peter M. Vallone of the NIST. Vallone, Development
>> of Multiplexed Assays for Evaluating SNP and STR Forensic Markers, National
>> Institute of Standards and Technology (NIST), 28 Feb 2003, slide 17."
>>
>> http://www.kerchner.com/dnamutationrates.htm
>>
>> Charles Kerchner
>> (P.E. Retired)
>> Emmaus PA USA
>> http://www.kerchner.com/dna-info.htm
>
>

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