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Archiver > GENEALOGY-DNA > 2007-12 > 1199066190


From: Kirsten Saxe <>
Subject: [DNA] Question for Thomas Krahn - was Re: Any news on the"Walk Through theY"initiative??(Theprocess, & a different approach)
Date: Sun, 30 Dec 2007 20:56:30 -0500
References: <11985d4c0712291203s44d3bd95l7abbffd6e7dafa01@mail.gmail.com><IGEOKAGLHNEKPCKPADIGEENIABAB.bbailey.lowedna@baileyconnection.com> <11985d4c0712291324ubd15c05sef7d91bc8b7994e@mail.gmail.com><00e501c84a62$8d998c80$6400a8c0@Ken1> <4778087C.1090103@comcast.net><008501c84b2c$d0896a90$6400a8c0@Ken1>
In-Reply-To: <008501c84b2c$d0896a90$6400a8c0@Ken1>


Hi Thomas,

One of your statements in the Walk on the Y slide presentation is
causing some confusion. Can you comment on your basis for the following
statement from one of the slides?

"If you're R1b1c like Craig Venter or James Watson you may expect about
2 private SNPS" to be found in a Walk on the Y.

That statement really struck me, in part because I was wondering along
the same lines as Ken does below. I've been guessing at explanations,
but of course your explanation would be most helpful.

I'd love to find a private SNP or two for one of my lines.

Kirsten Saxe

Ken Nordtvedt wrote:

>That's someone's statement, not an explanation. I'm looking for someone to
>go through their argument or derivation.
>
>If we use the "one SNP somewhere in the Y per father/son transmission"
>approximation which has been often used, then any of us has had about 200
>generations (6000 years) to produce private or family mutations or
>interesting clade-dividing SNPs in our male ancestral line. I think this is
>true for most any post-agriculture haplogroup which are roughly the same
>ages. To find 2 such SNPs will require looking at 1 percent of the Y one
>way or the other. That's a million nucleotide sites.
>
>Since I want to look for the clade-dividing SNPs, that requires somewhat
>more searching.
>
>Maybe Thomas will go through his numbers. Ken
>
>
>----- Original Message -----
>From: "Kirsten Saxe" <>
>To: <>
>Sent: Sunday, December 30, 2007 2:07 PM
>Subject: Re: [DNA] Any news on the "Walk Through
>theY"initiative??(Theprocess, & a different approach)
>
>
>
>
>>I don't know if this helps, but I think that around the time the Walk on
>>Y concept was first presented, Thomas Krahn said that an R1b or R1b1c
>>individual could expect to learn of 2 private SNPs from a walk on the Y.
>>Maybe he can comment on the prospects for Haplogroup I men, too.
>>
>>Kirsten
>>
>>Ken Nordtvedt wrote:
>>
>>
>>
>>>----- Original Message -----
>>>From: "Rebekah Canada" <>
>>>To: <>
>>>Sent: Saturday, December 29, 2007 2:24 PM
>>>Subject: Re: [DNA] Any news on the "Walk Through
>>>theY"initiative??(Theprocess, & a different approach)
>>>
>>>
>>>
>>>
>>>
>>>
>>>>We would want to run three samples from each cluster for the same
>>>>50,000 segment. If predictions are correct there will be on average
>>>>average average two SNPs per sample.
>>>>
>>>>
>>>>
>>>>
>>>How did you arrive at a predicted two SNPs per sample? And is this two
>>>per
>>>sample mutations relative to the other samples from the same cluster or
>>>same
>>>haplogroup, private mutations included, or relative to a distant standard
>>>
>>>
>>>from outside of your haplogroup?
>>
>>
>>>Ken
>>>
>>>
>>>
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>>>
>>>
>>>
>>>
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>>
>>
>
>
>
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