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Archiver > GENEALOGY-DNA > 2007-12 > 1199082025


From: "Alister John Marsh" <>
Subject: Re: [DNA] Question for Thomas Krahn - STRs in WOY regions
Date: Mon, 31 Dec 2007 19:20:25 +1300
References: <11985d4c0712291203s44d3bd95l7abbffd6e7dafa01@mail.gmail.com><IGEOKAGLHNEKPCKPADIGEENIABAB.bbailey.lowedna@baileyconnection.com> <11985d4c0712291324ubd15c05sef7d91bc8b7994e@mail.gmail.com><00e501c84a62$8d998c80$6400a8c0@Ken1> <4778087C.1090103@comcast.net><008501c84b2c$d0896a90$6400a8c0@Ken1><47784C4E.2040008@comcast.net>
In-Reply-To: <47784C4E.2040008@comcast.net>


Thomas,

I don't think I have asked this on the list before, but with the "Walk On
Y", will results be reported for any of the obscure STRs which are be in
that section of Y?

Apart from the 120 or so commonly commercially tested STRs, there are
apparently many more STRs scattered on Y. Many of these others have shorter
numbers of repeats, say 5 to 9 repeats. I presume these are mostly not
commercially tested, as they are thought to infrequently mutate. However, a
STR with say 5 to 9 repeats, may have mutated at least once in human
history. Some estimate in the order of 6,000,000,000 male births since Adam,
and if only 1% of those left male descendants, it is still a fair number of
opportunities for a short STR to have mutated at least once.

My guess is that in 50,000 base pairs, there might be several short STRs,
perhaps a few dozen if you include very short STRs and those with repeats of
2 or 3 bases.

I have previously expressed my interest in a test company offering to test a
panel of perhaps 50 or 100 ultra slow STRs. Perhaps WOY might produce some
of these as a byproduct of the SNP search.

It would be interesting if any STRs other than those commonly tested, were
reported in WOY results basically as a panel of ultra slow mutating STRs,
say STRs 68 to 77 or whatever. Whilst there would be few mutations, any
mutations found on those would be hugely important in indicating structure
to the Y Tree, even if they were not formally recognized as SNPs, and not
"officially" haplogroup clade defining.

In FTDNA's test runs on the WOY, I presume you would have covered ground
including some "lesser" STRs. Are you able to indicate if there might be
sufficient of these ultra slow STRs to form a significant panel, perhaps of
10 STRs?

John.


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