GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2007-12 > 1199149316


From: "Ron Scott" <>
Subject: Re: [DNA] Question for Thomas Krahn - STRs in WOY regions
Date: Mon, 31 Dec 2007 19:01:56 -0600


On Mon, 31 Dec 2007 14:02:29 EST, Ann writes:

> I'm not clear on the technology used by Knome, but I'm not at all sure that
> you can scale things down that way. Some of these new methods chop all the DNA
> in a cell sample into tiny pieces of a few hundred base pairs, sequence those
> short segments, and use computer techniques to align overlapping fragments
> into longer contiguous sequences. If that's what Knome is doing, there's no a
> priori way to say "just give me the Y."

I'm not clear either, but Ann Kiirikki at Knome has told me that this is "something we're wrestling with internally, but higher up ...., " referring to full-Y sequencing and other "limited services." I'm simply suggesting to Knome that there is a huge market of those who would want chr-Y sequencing, if they would offer it. Maybe, one of us could ask Ms. Kiirikki what sequencing method they use.

Ron Scott

This thread: