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Subject: Re: [DNA] Personal FTDNA mtDNA pages (was Revisit,case study 162-209-519...)
Date: Tue, 1 Jan 2008 13:41:18 EST
In a message dated 1/1/2008 8:15:05 AM Pacific Standard Time,
writes:
> So, in other words, if half of your body matches
> many others at HVR1, and you otherwise have
> exact matches at the FGS, you are still not
> considered having any matches on the personal
> page. That is a rather lonely existence,
> especially for those who go to all the trouble
> and expense of ordering the full sequence.
>
Kathy was speaking specifically of heteroplasmy, but close matches can be of
interest to everyone. As I wrote about my "marginal" mtDNA match, I had one
additional coding region mutation in my line compared to another FGS, whose
ancestral lines follow the same migration path from Middlesex Co, MA in the late
1600's to a Killingly, a small town in CT in the early 1700's. I do believe
we're within a one-generation gap of making a connection. Yet FTDNA does not
report this as a match.
I can understand the reasoning behind this, as those singleton differences
could have functional implications. However, a work-around is to encourage more
people to submit their sequences to GenBank, then use BLAST to find their
closest matches.
Ann Turner
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