GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2008-01 > 1199498846


From: "Dennis Wright" <>
Subject: Re: [DNA] SNP chasing using STSs
Date: Sat, 5 Jan 2008 13:07:26 +1100
In-Reply-To: <200801050117.m051GmAe002730@mail.rootsweb.com>


This image may help with what is and what is not heterochromatin.
http://nar.oxfordjournals.org/content/vol0/issue2007/images/large/gkm849f1.j
peg
or http://tinyurl.com/2faj4h
It appears there is a small region 57377045 to 57443438 that is Male
Specific towards the end of the heterochromatin zone.

Cheers
Dennis W

-----Original Message-----
From:
[mailto:]On Behalf Of Tim Janzen
Sent: Saturday, 5 January 2008 12:17 PM
To:
Subject: Re: [DNA] SNP chasing using STSs


Dear Dick,
I am simply following the Watson/Ventor/HUGO R1b1c male SNP trail
where it is leading us. I agree that we should in general be avoiding
heterochromatin. I don't know exactly what is in the region from position
57392694 to 57440935, but Watson, Ventor, and the HUGO R1b1c male do seem to
have quite a few SNPs that they share in that region. This region doesn't
appear to be heterochromatin or it wouldn't have been sequenced for Watson,
Ventor, and the HUGO R1b1c male. Thomas Krahn's Y browser indicates that
there are some genes in this region such as "C-terminal binding protein 2
pseudogene".
Sincerely,
Tim

-----Original Message-----
From:
[mailto:] On Behalf Of RICHARD KENYON
Sent: Friday, January 04, 2008 4:12 PM
To:
Subject: [DNA] SNP chasing using STSs

Tim,
I'm surprised by the locations of some of the SNPs in your list.
Shouldn't we only look in the "Male-Specific Y" (MSY) regions and portions
that are not heterogeneous chromatin? Gareth gave a recent reference to a
useful paper, "MSY Breakpoint Mapper, a database of sequence-tagged sites
useful in defining naturally occurring deletions in the human Y chromosome"
by Lange et al., Nucleic Acids Research, 2007, pp. 1-7.

Richard R. Kenyon ("Dick")


-------------------------------
To unsubscribe from the list, please send an email to
with the word 'unsubscribe' without the
quotes in the subject and the body of the message

This thread: